Publications
The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA.
LeRoux, M., Srikant, S., Teodoro, G.I.C,. Zhang, T., Littlehale, M.L., Doron, S., Badiee, M., Leung, A.K.L., Sorek, R., Laub, M.T.
(2022) Nature Microbiology, Jul;7(7):1028-1040. https://doi.org/10.1038/s41564-022-01153-5
Publications can also be viewed at pubmed.
Toxin-Antitoxin Systems as Phage Defense Elements.
LeRoux, M., Laub, M.T.
(2022) Annual Review of Microbiology. Apr 8. doi: 10.1146/annurev-micro-020722-013730.
Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin.
LeRoux, M., Culviner, P. H., Liu, Y. J., Littlehale, M. L., & Laub, M. T.
(2020). Molecular Cell, 79(2), 280-292.e8.
LeRoux, M., Peterson, S.B., Mougous, J.D.
(2015) Bacterial Danger Sensing. Journal of Molecular Biology. 427(23), 3744-53.
Whitney, J.C., Quentin, D., Sawai, S., LeRoux, M., Harding, B.N., Ledvina, H.E., Tran B., Robinson, H., Goo Y.A., Goodlett, D.R., Raunser, S., and Mougous, J.D.
(2015) Cell. 163(3), 607-19.
A self-lysis pathway that enhances the virulence of a pathogenic bacterium.
McFarland, K. A., Dolben, E. L., LeRoux, M., Kambara, T. K., Ramsey, K. M., Kirkpatrick, R. L., Mougous J.D., Hogan D.A., and Dove S.L.
(2015) Proceedings of the National Academy of Sciences. 112(27), 8433-8438.
LeRoux, M., Kirkpatrick, R.L., Montauti E.I., Peterson S.B., Harding B.N., Whitney, J.C., Russell A.B., Traxler, B., Goo, Y.A., Goodlett, D.R., Wiggins, P.A., and Mougous, J.D.
(2015) eLife. 4, e05701.
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
Russell, A. B., LeRoux, M., Hathazi, K., Agnello, D. M., Ishikawa, T., Wiggins, P. A., Wai, S.N., and Mougous, J.D.
(2013). Nature. 496(7446), 508-512.
LeRoux, M., De Leon, J. A., Kuwada, N. J., Russell, A. B., Pinto-Santini, D., Hood, R. D., Agnello, D.M., Robertson, S.M., Wiggins, P.A., and Mougous, J.D.
(2012). Proceedings of the National Academy of Sciences, 109(48), 19804–19809.
Chou S., Bui N.K., Russell A.B., Lexa K., Gardiner, T., LeRoux M., Vollmer W., Mougous J.D.
(2012) Cell Reports 1, 1–9.
Type VI secretion delivers bacteriolytic effectors to target cells.
Russell A.B., Hood R.D., Bui N.K., LeRoux M., Vollmer W., Mougous J.D.
(2011) Nature. 475(7356), 343-347.
Ndiaye, D., Patel, V., Demas, A., LeRoux, M., Ndir, O., Mboup, S., Clardy, J., et. al.
(2010). The American journal of tropical medicine and hygiene, 82(2), 228–230.
Plasmodium falciparum biology: analysis of in vitro versus in vivo growth conditions.
LeRoux, M., Lakshmanan, V., & Daily, J. P.
(2009). Trends in parasitology, 25(10), 474–481.
Ingram, K. K., Krummey, S., & LeRoux, M.
(2009). BMC ecology, 9, 7.